منابع مشابه
Relative aldosterone excess: relative to what?
There is clear evidence that the vessel wall is an aldosterone target tissue, and that aldosterone at physiological levels produces vasoconstriction by genomic and rapid nongenomic actions.1 Similarly, in clinical studies cited by Duffy et al,2 patients with primary aldosteronism show impaired flow-mediated dilatation among other indices of endothelial dysfunction;3,4 in addition, mineralocorti...
متن کاملRole of angiotensinogen and relative aldosterone excess in salt-sensitive hypertension.
Role of Angiotensinogen and Relative Aldosterone Excess in Salt-Sensitive Hypertension To the Editor: We read with great interest the article by Michel et al. They demonstrated that circulating angiotensinogen concentration (AGT) was positively associated with aldosterone level and blood pressure in subjects of African ancestry with high urinary Na/K ratio. Their findings may elucidate one of t...
متن کاملLow-renin hypertension with relative aldosterone excess is associated with impaired NO-mediated vasodilation.
Recent studies suggest that hypertension associated with low renin status and hyperaldosteronism is associated with increased risk for end-organ damage and cardiovascular events compared with other forms of hypertension. Additionally, experimental studies have demonstrated impaired nitric oxide-mediated bioactivity in these states. To investigate the relation between renin/aldosterone status an...
متن کاملRectal potential difference in the diagnosis of aldosterone excess.
Rectal potential difference (pd) is directly related to the plasma aldosterone concentration, and rises when aldosterone is stimulated by sodium deprivation. However, when the measurement of rectal pd was tested at a screening test for hyperaldosteronism in 19 hypertensive subjects, four of the eight with primary hyperaldosteronism had a normal pd and four of the eight without aldosterone exces...
متن کاملAldosterone excess, hypertension, and chromosome 7p22: evidence continues to mount.
In recent years, numerous groups of investigators have reported primary aldosteronism (PAL) to be much more common than previously thought.1–4 This has followed recognition of the aldosterone/renin ratio (ARR) as an improved, more sensitive method of screening for PAL and the application of ARR testing to a wider population, to include normokalemic, as well as hypokalemic, hypertensive subjects...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Hypertension
سال: 2005
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.0000184227.75221.6e